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1995 1
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2002 2
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2004 3
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2008 3
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The following terms were not found in PubMed: Cleaved-Asp175, Cleaved-D175
Page 1
Decreased cyclooxygenase-2 associated with impaired megakaryopoiesis and thrombopoiesis in primary immune thrombocytopenia.
Zhuang X, Xu P, Ou Y, Shao X, Li Y, Ma Y, Qin S, Hua F, Zhan Y, Ji L, Qiao T, Chen H, Cheng Y. Zhuang X, et al. J Transl Med. 2023 Aug 12;21(1):540. doi: 10.1186/s12967-023-04389-9. J Transl Med. 2023. PMID: 37573325 Free PMC article.
The participation of COX-2 in the maturation of megakaryocytes has been reported but barely studied in primary immune thrombocytopenia (ITP). METHODS: The expressions of COX-2 and Caspase-1, Caspase-3 and Caspase-3 p17 subunit in platelet …
The participation of COX-2 in the maturation of megakaryocytes has been reported but barely studied in primary immune thrombocytopenia (ITP) …
Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.
Shay JW, Homma N, Zhou R, Naseer MI, Chaudhary AG, Al-Qahtani M, Hirokawa N, Goudarzi M, Fornace AJ Jr, Baeesa S, Hussain D, Bangash M, Alghamdi F, Schulten HJ, Carracedo A, Khan I, Qashqari H, Madkhali N, Saka M, Saini KS, Jamal A, Al-Maghrabi J, Abuzenadah A, Chaudhary A, Al Qahtani M, Damanhouri G, Alkhatabi H, Goodeve A, Crookes L, Niksic N, Beauchamp N, Abuzenadah AM, Vaught J, Budowle B, Assidi M, Buhmeida A, Al-Maghrabi J, Buhmeida A, Assidi M, Merdad L, Kumar S, Miura S, Gomez K, Carracedo A, Rasool M, Rebai A, Karim S, Eldin HFN, Abusamra H, Alhathli EM, Salem N, Al-Qahtani MH, Kumar S, Faheem H, Agarwa A, Nieschlag E, Wistuba J, Damm OS, Beg MA, Abdel-Meguid TA, Mosli HA, Bajouh OS, Abuzenadah AM, Al-Qahtani MH, Coskun S, Abu-Elmagd M, Buhmeida A, Dallol A, Al-Maghrabi J, Hakamy S, Al-Qahtani W, Al-Harbi A, Hussain S, Assidi M, Al-Qahtani M, Abuzenadah A, Ozkosem B, DuBois R, Messaoudi SS, Dandana MT, Mahjoub T, Almawi WY, Abdalla S, Al-Aama MN, Elzawahry A, Takahashi T, Mimaki S, Furukawa E, Nakatsuka R, Kurosaka I, Nishigaki T, Nakamura H, Serada S, Naka T, Hirota S, Shibata T, Tsuchihara K, Nishida T, Kato M, Mehmood S, Ashraf NM, Asif A, Bilal M, Mehmood MS, Hussain … See abstract for full author list ➔ Shay JW, et al. BMC Genomics. 2016 Jul 20;17 Suppl 6(Suppl 6):487. doi: 10.1186/s12864-016-2858-0. BMC Genomics. 2016. PMID: 27454254 Free PMC article.
Sabanegh, Mourad Assidi, Mohammed Al-Qahtani P40 Significant protein profile alterations in men with primary and secondary infertility Ashok Agarwal, Rakesh Sharma, Luna Samanta, Damayanthi Durairajanayagam, Mourad Assidi, Muhammad Abu-Elmagd, Mohammed Al-Qahtani, Adel M. …
Sabanegh, Mourad Assidi, Mohammed Al-Qahtani P40 Significant protein profile alterations in men with primary and secondary infertilit …
Calpain-1 cleaves and activates caspase-7.
Gafni J, Cong X, Chen SF, Gibson BW, Ellerby LM. Gafni J, et al. J Biol Chem. 2009 Sep 11;284(37):25441-9. doi: 10.1074/jbc.M109.038174. Epub 2009 Jul 18. J Biol Chem. 2009. PMID: 19617626 Free PMC article.
Here, we present that recombinant caspase-7 is directly cleaved by calpain-1 within the large subunit of caspase-7 to produce two novel products, large subunit p18 and p17. This new form of caspase-7 has a 6-fold increase in V(max) when compared with the prev …
Here, we present that recombinant caspase-7 is directly cleaved by calpain-1 within the large subunit of caspase-7 to produce two nov …
A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro.
Han Z, Hendrickson EA, Bremner TA, Wyche JH. Han Z, et al. J Biol Chem. 1997 May 16;272(20):13432-6. doi: 10.1074/jbc.272.20.13432. J Biol Chem. 1997. PMID: 9148968 Free article.
The apoptotic cysteine protease, caspase-3, is expressed in cells as an inactive 32-kDa precursor from which 17 kDa (p17) and 12 kDa (p12) subunits of the mature caspase-3 are proteolytically generated during apoptosis. ...This indicated …
The apoptotic cysteine protease, caspase-3, is expressed in cells as an inactive 32-kDa precursor from which 17 kDa (p17 …
Inhibition of caspase-3 activity and activation by protein glutathionylation.
Huang Z, Pinto JT, Deng H, Richie JP Jr. Huang Z, et al. Biochem Pharmacol. 2008 Jun 1;75(11):2234-44. doi: 10.1016/j.bcp.2008.02.026. Epub 2008 Feb 29. Biochem Pharmacol. 2008. PMID: 18395187 Free PMC article.
Proteolytic activation of caspases was also affected, as the activation of procaspase-3 and procaspase-9 in HL-60 cell extracts induced by cytochrome c and dATP was inhibited by pre-incubation with GSSG. When biotin-labeled GSSG was incubated with recombinant caspase-3 …
Proteolytic activation of caspases was also affected, as the activation of procaspase-3 and procaspase-9 in HL-60 cell extracts induced by c …
The apoptotic cysteine protease CPP32.
Kumar S. Kumar S. Int J Biochem Cell Biol. 1997 Mar;29(3):393-6. doi: 10.1016/s1357-2725(96)00146-x. Int J Biochem Cell Biol. 1997. PMID: 9202418 Review.
CPP32 has been consistently implicated as a key protease of the ICE/CED-3 family that is activated in response to a variety of death stimuli. Active CPP32 consists of P17 and p12 subunits derived from a 32 kDa pro-enzyme. This activation can be mediated by some ICE- …
CPP32 has been consistently implicated as a key protease of the ICE/CED-3 family that is activated in response to a variety of death stimuli …
Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: any single lysine or lysine pair of the small subunit is sufficient for ubiquitination.
Chen L, Smith L, Wang Z, Smith JB. Chen L, et al. Mol Pharmacol. 2003 Aug;64(2):334-45. doi: 10.1124/mol.64.2.334. Mol Pharmacol. 2003. PMID: 12869638
This result suggests that caspase-3 subunits, in contrast to the zymogen, are unstable because of degradation by the ubiquitin-proteasome system. ...Lactacystin treatment of HL-60 cells induced proteolytic processing of the X-linked inhibitor of apoptosis (XI …
This result suggests that caspase-3 subunits, in contrast to the zymogen, are unstable because of degradation by the ub …
The regulatory role of the RANKL/RANK/OPG signaling pathway in the mechanisms of tooth eruption in patients with impacted teeth.
Brodetska L, Natrus L, Lisakovska O, Kaniura O, Iakovenko L, Skrypnyk I, Flis P. Brodetska L, et al. BMC Oral Health. 2020 Sep 18;20(1):261. doi: 10.1186/s12903-020-01251-y. BMC Oral Health. 2020. PMID: 32948158 Free PMC article.
Levels of RANKL, RANK, OPG, osteocalcin (OC), NF-kappaB p65 subunit, NFATc1, and caspase-3 were determined by western blotting. ...In the area of IT, we observed an increase in procaspase-3 and p17 levels (1.32 and 1.78 folds). This reflects impairment …
Levels of RANKL, RANK, OPG, osteocalcin (OC), NF-kappaB p65 subunit, NFATc1, and caspase-3 were determined by western b …
Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s).
Kamada S, Kikkawa U, Tsujimoto Y, Hunter T. Kamada S, et al. J Biol Chem. 2005 Jan 14;280(2):857-60. doi: 10.1074/jbc.C400538200. Epub 2004 Nov 29. J Biol Chem. 2005. PMID: 15569692 Free article.
Here we confirmed nuclear localizations for both caspase-3-p17 and caspase-3-p12 subunits of active caspase in apoptotic cells using subcellular fractionation analysis. ...Mutations at the cleavage site between the p17 and p12 s …
Here we confirmed nuclear localizations for both caspase-3-p17 and caspase-3-p12 subunits of activ …
Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage.
Fujikawa DG, Ke X, Trinidad RB, Shinmei SS, Wu A. Fujikawa DG, et al. J Neurochem. 2002 Oct;83(1):229-40. doi: 10.1046/j.1471-4159.2002.01152.x. J Neurochem. 2002. PMID: 12358747 Free article.
Some 6-8 h after methamphetamine treatment, thymocytes showed apoptosis by electron-microscopic examination, positive terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL), DNA laddering, cleavage of caspase-3 into its active p17 subunit …
Some 6-8 h after methamphetamine treatment, thymocytes showed apoptosis by electron-microscopic examination, positive terminal deoxynucleoti …
60 results